Clarkson's rehabilitation research is based on an integrated approach that draws on its expertise and resources in engineering, business, science and physical therapy. Recent research collaborations include: the development of a biosensor that can be worn in a shoe to reduce falls in at-risk populations; the application of virtual reality to assist in post-stroke rehabiliation, and a computer software system that can map the progression of Parkinson's Disease.

 The development of artificial heart valves, artificial veins, and non-reactive coatings for medical implants such as artifical knees. A drug delivery systems that relies on controlled particle size and shape, and biologically active surfaces. Virtual wheelchairs to assist persons with diabilities.  coatings for artificial knees, heart valve replacements

Clarkson combines expertise in  engineering, biomaterials, and physical therapy to develop methods and materials that enhance rehabilitation, occupational health and new medical technologies. The goal is to develop technology that will improve the quality of life for a number of individuals. 

At Clarkson's Center for Rehabilitation Engineering, Science and Technology (CREST), biotechnology, physical therapy, science and assistive technology come together to improve lives impacted by injury or disease.